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About Alpha-1

Alpha-1 antitrypsin (sometimes called AAT) is made in the liver by the body. It protects the lungs from damage due to things like infection or smoke. 1,2

If you have Alpha-1, you have very low levels of Alpha-1 antitrypsin, meaning that your lungs don't have the same protection as those of healthy people. You also have a higher risk for emphysema. 1,2

Alpha-1 is an inherited disease. It is often confused with asthma or smoking-related COPD (chronic bronchitis or emphysema). 1,2

Because Alpha-1 is so much like asthma, it can take a long time to identify. On average, patients with Alpha-1 will see 3 doctors over 7 years before they are diagnosed. 2

This is because the symptoms of Alpha-1 and asthma are almost the same 1:

  • Shortness of breath
  • Long-term cough
  • Problems breathing
  • Wheezing
Could your symptoms be caused by Alpha-1? Click here to find out.

1. Alpha-1 Foundation - What is Alpha-1? Alpha-1 Fast Facts. Available at: Alphaone.org. Accessed on September 16, 2009.
2. COPD International Network-You Are Not Alone. Available at: http://www.copdinternational.com/Library/alpha-1.htm. Accessed on September 16, 2009.
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