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Alpha-1 Screener
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Symptoms of Alpha-1

The following symptoms could mean that you have Alpha-1 Antitrypsin Deficiency:


  • Early onset of emphysema (at age 45 or younger)
  • COPD – emphysema, chronic bronchitis, or bronchiectasis (inability to clear congestion/frequent lung infections)
  • Symptoms beginning between the ages of 25 and 50
  • Asthma – not fully reversible with asthma medication/inhalers
  • Shortness of breath (with routine activity or at rest)
  • Frequent cough – with or without mucus
  • Wheezing
  • Liver disease with no known cause
  • Necrotizing panniculitis (looks like raised red spots on the skin)
  • Family history of COPD (emphysema), liver disease, or unexplained death
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